Alicia Keys, accepting her Grammy award for Best Female R&B Vocal Performance for “No One,” awarded by the late Prince at the 50th GRAMMY Awards at the Staples Center in Los Angeles on February 10, 2008.

“No One” won her Best Female R&B Vocal Performance, winning over Jill Scott and Mary J. Blige, and for Best R&B Song.

The big 50th honored The Recording Academy’s legacy and paid tribute to its future with a list of honorees and performers. The primary ceremonies were televised in the US on CBS. Alicia was the evening's opening musician, duetting on piano with a half-century old clip of Frank Sinatra for "Learnin' The Blues.”

She returned to the stage to perform "No One,” lifting the audience higher as she brought out guitarist John Mayer onstage for a melodic guitar solo.